4.6 Article

Generation of multilayered structures for biomedical applications using a novel tri-needle coaxial device and electrohydrodynamic flow

期刊

JOURNAL OF THE ROYAL SOCIETY INTERFACE
卷 5, 期 27, 页码 1255-1261

出版社

ROYAL SOC
DOI: 10.1098/rsif.2008.0247

关键词

electrohydrodynamic; biomedical; layered structures

资金

  1. EPSRC [EP/E045839]
  2. Royal Academy of Engineering
  3. Royal Society
  4. Engineering and Physical Sciences Research Council [EP/F031122/1, EP/E045839/1] Funding Source: researchfish
  5. EPSRC [EP/F031122/1, EP/E045839/1] Funding Source: UKRI

向作者/读者索取更多资源

In this short communication, we describe the scope and flexibility of using a novel device containing three coaxially arranged needles to form a variety of novel morphologies. Different combinations of materials are subjected to controlled flow through the device under the influence of an applied electric field. The resulting electrohydrodynamic flow allows us to prepare double-layered bubbles, porous encapsulated threads and nanocapsules containing three layers. The ability to process such multilayered structures is very significant for biomedical engineering applications, for example, generating capsules for drug delivery, which can provide multistage controlled release.

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