期刊
JOURNAL OF THE ROYAL SOCIETY INTERFACE
卷 5, 期 26, 页码 957-975出版社
ROYAL SOC
DOI: 10.1098/rsif.2008.0071
关键词
biomaterials; nerve repair; neural prosthetics
资金
- NIDCD NIH HHS [R01 DC006849, DC06849] Funding Source: Medline
- NINDS NIH HHS [R01 NS45072, R01 NS043486, R01 NS044409, NS44409, R01 NS045072, NS43486] Funding Source: Medline
Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and ( v) neural stem cell encapsulation for neurotrauma. The biological and material requirements for the biomaterials in these applications are discussed. The difficulties that the biomaterials might face in each application and the possible solutions are also reviewed in this article.
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