相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma
Michael A. Postow et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Radiotherapy with or without Chemotherapy in Muscle-Invasive Bladder Cancer
Nicholas D. James et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
The immune contexture in human tumours: impact on clinical outcome
Wolf Herman Fridman et al.
NATURE REVIEWS CANCER (2012)
Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers
K. J. Harrington et al.
BRITISH JOURNAL OF CANCER (2011)
The Efficacy of Radiotherapy Relies upon Induction of Type I Interferon-Dependent Innate and Adaptive Immunity
Byron C. Burnette et al.
CANCER RESEARCH (2011)
Adaptive Clinical Trials: The Promise and the Caution
Donald A. Berry
JOURNAL OF CLINICAL ONCOLOGY (2011)
On the Usefulness of Outcome-Adaptive Randomization Reply
Edward L. Korn et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Randomized Phase II Study of Pemetrexed, Carboplatin, and Thoracic Radiation With or Without Cetuximab in Patients With Locally Advanced Unresectable Non-Small-Cell Lung Cancer: Cancer and Leukemia Group B Trial 30407
Ramaswamy Govindan et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Outcome-Adaptive Randomization: Is It Useful?
Edward L. Korn et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Randomized Phase II Trials: A Long-term Investment With Promising Returns
Manish R. Sharma et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2011)
All-Comers versus Enrichment Design Strategy in Phase II Trials
Sumithra J. Mandrekar et al.
JOURNAL OF THORACIC ONCOLOGY (2011)
Practical modifications to the time-to-event continual reassessment method for phase I cancer trials with fast patient accrual and late-onset toxicities
Mei-Yin C. Polley
STATISTICS IN MEDICINE (2011)
Targeting hypoxia in cancer therapy
William R. Wilson et al.
NATURE REVIEWS CANCER (2011)
Modulating Tumor Vasculature through Signaling Inhibition to Improve Cytotoxic Therapy
Amit Maity et al.
CANCER RESEARCH (2010)
Performing Phase I Clinical Trials of Anticancer Agents: Perspectives from within the European Union and Japan
Martin D. Forster et al.
CLINICAL CANCER RESEARCH (2010)
Information Needed to Conduct First-in-Human Oncology Trials in the United States: A View from a Former FDA Medical Reviewer
Adrian M. Senderowicz
CLINICAL CANCER RESEARCH (2010)
GCP Data Quality for Early Clinical Development
Edwin P. Rock et al.
CLINICAL CANCER RESEARCH (2010)
Phase I Clinical Trials: Overcoming Barriers
Susan E. Bates
CLINICAL CANCER RESEARCH (2010)
An Overview of the Optimal Planning, Design, and Conduct of Phase I Studies of New Therapeutics
Patricia M. LoRusso et al.
CLINICAL CANCER RESEARCH (2010)
Approaches to Phase 1 Clinical Trial Design Focused on Safety, Efficiency, and Selected Patient Populations: A Report from the Clinical Trial Design Task Force of the National Cancer Institute Investigational Drug Steering Committee
S. Percy Ivy et al.
CLINICAL CANCER RESEARCH (2010)
The Design of Phase II Clinical Trials Testing Cancer Therapeutics: Consensus Recommendations from the Clinical Trial Design Task Force of the National Cancer Institute Investigational Drug Steering Committee
Lesley Seymour et al.
CLINICAL CANCER RESEARCH (2010)
Targeted Cancer Therapies in the Twenty-First Century: Lessons From Imatinib
F. Stegmeier et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2010)
Toxicity of Phase I Radiation Oncology Trials: Worldwide Experience
C. Glass et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2010)
Stereotactic Body Radiation Therapy for Inoperable Early Stage Lung Cancer
Robert Timmerman et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)
More Lessons Learned From the Suffocation of Hypoxia
K. Kian Ang
JOURNAL OF CLINICAL ONCOLOGY (2010)
Tirapazamine, Cisplatin, and Radiation Versus Cisplatin and Radiation for Advanced Squamous Cell Carcinoma of the Head and Neck (TROG 02.02, HeadSTART): A Phase III Trial of the Trans-Tasman Radiation Oncology Group
Danny Rischin et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Comparison of Error Rates in Single-Arm Versus Randomized Phase II Cancer Clinical Trials
Hui Tang et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Hypofractionated Stereotactic Radiation Therapy: An Effective Therapy for Recurrent High-Grade Gliomas
Shannon E. Fogh et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme
David M. Peereboom et al.
JOURNAL OF NEURO-ONCOLOGY (2010)
Randomized Clinical Trials With Biomarkers: Design Issues
Boris Freidlin et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
Randomized Phase II Trials Time for a New Era in Clinical Trial Design
Sumithra J. Mandrekar et al.
JOURNAL OF THORACIC ONCOLOGY (2010)
Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
James A. Bonner et al.
LANCET ONCOLOGY (2010)
Clinical trial designs for evaluating the medical utility of prognostic and predictive biomarkers in oncology
Richard Simon
PERSONALIZED MEDICINE (2010)
I-SPY 2: An Adaptive Breast Cancer Trial Design in the Setting of Neoadjuvant Chemotherapy
A. D. Barker et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2009)
Optimising the design of phase II oncology trials: The importance of randomisation
Mark J. Ratain et al.
EUROPEAN JOURNAL OF CANCER (2009)
QUALITY OF RADIOTHERAPY REPORTING IN RANDOMIZED CONTROLLED TRIALS OF HODGKIN'S LYMPHOMA AND NON-HODGKIN'S LYMPHOMA: A SYSTEMATIC REVIEW
Justin E. Bekelman et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2009)
AMERICAN SOCIETY FOR RADIATION ONCOLOGY (ASTRO) SURVEY OF RADIATION BIOLOGY EDUCATORS IN US AND CANADIAN RADIATION ONCOLOGY RESIDENCY PROGRAMS
Barry S. Rosenstein et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2009)
THE GROWTH OF ACADEMIC RADIATION ONCOLOGY: A SURVEY OF ENDOWED PROFESSORSHIPS IN RADIATION ONCOLOGY
Todd H. Wasserman et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2009)
DETECTING VASCULAR-TARGETING EFFECTS OF THE HYPOXIC CYTOTOXIN TIRAPAZAMINE IN TUMOR XENOGRAFTS USING MAGNETIC RESONANCE IMAGING
Lauren J. Bains et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2009)
Phase II Trials in Journal of Clinical Oncology
Stephen A. Cannistra
JOURNAL OF CLINICAL ONCOLOGY (2009)
RTOG 0017: A Phase I Trial of Concurrent Gemcitabine/Carboplatin or Gemcitabine/Paclitaxel and Radiation Therapy (Ping-Pong Trial) Followed By Adjuvant Chemotherapy for Patients with Favorable Prognosis Inoperable Stage IIIA/B Non-small Cell Lung Cancer
Hak Choy et al.
JOURNAL OF THORACIC ONCOLOGY (2009)
Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial
Robert Pirker et al.
LANCET (2009)
The advancement of translational medicine-from regional challenges to global solutions
Salvatore Albani et al.
NATURE MEDICINE (2009)
High rate of severe radiation dermatitis during radiation therapy with concurrent cetuximab in head and neck cancer: Results of a survey in EORTC institutes
Christian Giro et al.
RADIOTHERAPY AND ONCOLOGY (2009)
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients
Jean-Pierre Pignon et al.
RADIOTHERAPY AND ONCOLOGY (2009)
The FDA critical path initiative and its influence on new drug development
Janet Woodcock et al.
ANNUAL REVIEW OF MEDICINE (2008)
A prospective pilot study of curative-intent stereotactic body radiation therapy in patients with 5 or fewer oligometastatic lesions
Michael T. Milano et al.
CANCER (2008)
Multi-arm clinical trials of new agents: Some design considerations
Boris Freidlin et al.
CLINICAL CANCER RESEARCH (2008)
Processes for quality improvements in radiation oncology clinical trials
T. J. Fitzgerald et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2008)
Performing nondiagnostic research biopsies in irradiated tissue: A review of scientific, clinical, and ethical considerations
Aaron P. Brown et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Reducing Uncertainties About the Effects of Chemoradiotherapy for Cervical Cancer: A Systematic Review and Meta-Analysis of Individual Patient Data From 18 Randomized Trials
Claire Vale et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Speeding up the evaluation of new agents in cancer
Mahesh K. B. Parmar et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)
Exploring vascular dysfunction caused by tirapazamine
Lynsey A. Huxham et al.
MICROVASCULAR RESEARCH (2008)
Platinum-based chemotherapy plus cetuximab in head and neck cancer
Jan B. Vermorken et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Normal tissue toxicity after small field hypofractionated stereotactic body radiation
Michael T. Milano et al.
RADIATION ONCOLOGY (2008)
Modes of resistance to anti-angiogenic therapy
Gabriele Bergers et al.
NATURE REVIEWS CANCER (2008)
Cetuximab for the treatment of colorectal cancer
Derek J. Jonker et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
The role of mTOR inhibition in augmenting radiation induced autophagy
Jerry. J. Jaboin et al.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2007)
Hypoxic radiosensitization: Adored and ignored
Jens Overgaard
JOURNAL OF CLINICAL ONCOLOGY (2007)
Bioreductive drugs: from concept to clinic
S. R. McKeown et al.
CLINICAL ONCOLOGY (2007)
The hypoxic tumour microenvironment, patient selection and hypoxia-modifying treatments
I. J. Hoogsteen et al.
CLINICAL ONCOLOGY (2007)
Exploitable mechanisms for combining drugs with radiation: concepts, achievements and future directions
Soren M. Bentzen et al.
NATURE CLINICAL PRACTICE ONCOLOGY (2007)
Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells
Carolyn Cao et al.
CANCER RESEARCH (2006)
Designing dose-escalation trials with late-onset toxicities using the time-to-event continual reassessment method
Daniel Normolle et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
JA Bonner et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Tirapazamine causes vascular dysfunction in HCT-116 tumour xenografts
LA Huxham et al.
RADIOTHERAPY AND ONCOLOGY (2006)
Is translational research compatible with preclinical publication strategies?
Stig Linder et al.
RADIATION ONCOLOGY (2006)
Phase III trial of paclitaxel plus carboplatin with or without tirapazamine in advanced non-small-cell lung cancer: Southwest Oncology Group Trial S0003
SK Williamson et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Kinetics of response to long-term treatment combining pentoxifylline and tocopherol in patients with superficial radiation-induced fibrosis
S Delanian et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Design issues of randomized phase II trials and a proposal for phase II screening trials
LV Rubinstein et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Enhanced radiation damage of tumor vasculature by mTOR inhibitors
ET Shinohara et al.
ONCOGENE (2005)
Hypoxia-induced dedifferentiation of tumor cells -: A mechanism behind heterogeneity and aggressiveness of solid tumors
H Axelson et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2005)
Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity
K Dittmann et al.
RADIOTHERAPY AND ONCOLOGY (2005)
Randomized trial of amifostine in locally advanced non-small-cell lung cancer patients receiving chemotherapy and hyperfractionated radiation: Radiation Therapy Oncology Group trial 98-01
B Movsas et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Tirapazamine, cisplatin, and radiation versus fluorouracil, cisplatin, and radiation in patients with locally advanced head and neck cancer: A randomized phase II trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02)
D Rischin et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Clinical studies of hypoxia modification in radiotherapy
JHAM Kaanders et al.
SEMINARS IN RADIATION ONCOLOGY (2004)
Evaluating the efficiency of targeted designs for randomized clinical trials
R Simon et al.
CLINICAL CANCER RESEARCH (2004)
Early selection in a randomized phase II clinical trial
SM Steinberg et al.
STATISTICS IN MEDICINE (2002)
Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction.
JS Macdonald et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
A flexible design for multiple armed screening trials
DJ Sargent et al.
STATISTICS IN MEDICINE (2001)
Radiation concurrent with gemcitabine for locally advanced head and neck cancer: A phase I trial and intracellular drug incorporation study
A Eisbruch et al.
JOURNAL OF CLINICAL ONCOLOGY (2001)
Sequential designs for phase I clinical trials with late-onset toxicities
YK Cheung et al.
BIOMETRICS (2000)
分享论文
