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Alex R. Shoemaker et al.
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Judith G. Villablanca et al.
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Upregulation of Bfl-1/A1 in leukemia cells undergoing differentiation by all-trans retinoic acid treatment attenuates chemotherapeutic agent-induced apoptosis
L. Xia et al.
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G Tabellini et al.
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JC Reed et al.
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T Oltersdorf et al.
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B Yang et al.
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Phase II trial of fenretinide in advanced renal carcinoma
U Vaishampayan et al.
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N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines
M Cuello et al.
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Phase II study of Fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American brain tumor consortium study
VK Puduvalli et al.
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Fenretinide induces sustained-activation of JNK/p38 MAPK and apoptosis in a reactive oxygen species-dependent manner in neuroblastoma cells
S Osone et al.
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Phosphorylation and inactivation of myelbid cell leukemia 1 by JNK in response to oxidative stress
S Inoshita et al.
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Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis
SR Datta et al.
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PH O'Donnell et al.
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The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs)
RK Barr et al.
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Retinoid therapy of childhood cancer
CP Reynolds et al.
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BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
EHYA Cheng et al.
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Short tandem repeat profiling provides an international reference standard for human cell lines
JR Masters et al.
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MC Wei et al.
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Chemoprevention of breast cancer with fenretinide
R Torrisi et al.
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BJ Maurer et al.
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Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
SJ Korsmeyer et al.
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