期刊
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
卷 37, 期 -, 页码 48-55出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jmbbm.2014.05.005
关键词
Hernia; Polypropylene mesh; Mechanical properties; Anisotropy; Viscoelasticity
The use of synthetic polypropylene mesh for hernia surgical repair and the correction of female pelvic organ prolapse have been controversial due to increasing post-operative complications, including mesh erosion, chronic pain, infection, and support failure. These morbidities may be related to a mismatch of mechanical properties between soft tissues and the mesh. The aim of this study was to gain a better understanding of the biomechanical behavior of Prolene polypropylene mesh (Ethicon, Sommerville, NJ, USA), which is widely used for a variety of surgical repair procedures. The stiffness and permanent deformation of Prolene mesh were compared in different directions by performing uniaxial tensile failure tests, cyclic and creep tests at simulated physiological loads in the coursewise (0 degrees), walewise (90 degrees) and the diagonal (45 degrees) directions. Failure tests suggest that the mechanical properties of the mesh is anisotropic; with response at 0 degrees being the most compliant while 90 degrees was the stiffest. Irreversible deformation and viscoelastic behavior were observed in both cyclic and creep tests. The anisotropic property may be relevant to the placement of mesh in surgery to maximize long term mesh performance. The considerable permanent deformation may be associated with an increased risk of post-operative support failure. (C) 2014 Elsevier Ltd. All rights reserved.
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