期刊
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
卷 17, 期 6, 页码 998-1005出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1355617711000531
关键词
Cognition; Cognitive reserve; Aging; Social behavior; Life Style; Risk reduction behavior; Longitudinal studies; Epidemiology
资金
- Illinois Department of Public Health
- National Institute on Aging [R01AG17917, R01AG024871, R01AG22018]
- Robert C. Borwell Endowment Fund
We examined the association of social activity with cognitive decline in 1138 persons without dementia at baseline with a mean age of 79.6 (SD=7.5) who were followed for up to 12 years (mean=5.2; SD=2.8). Using mixed models adjusted for age, sex, education, race, social network size, depression, chronic conditions, disability, neuroticism, extraversion, cognitive activity, and physical activity, more social activity was associated with less cognitive decline during average follow-up of 5.2 years (SD=2.7). A one point increase in social activity score (range=1-4.2; mean = 2.6; SD=0.6) was associated with a 47% decrease in the rate of decline in global cognitive function (p,. 001). The rate of global cognitive decline was reduced by an average of 70% in persons who were frequently socially active (score=3.33, 90(th) percentile) compared to persons who were infrequently socially active (score=1.83, 10(th) percentile). This association was similar across five domains of cognitive function. Sensitivity analyses revealed that individuals with the lowest levels of cognition or with mild cognitive impairment at baseline did not drive this relationship. These results confirm that more socially active older adults experience less cognitive decline in old age. (JINS, 2011, 17, 998-1005)
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