期刊
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
卷 17, 期 2, 页码 364-368出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1355617710001633
关键词
Hypoxia-ischemia; Brain; Amnesia; Executive functions; Psychomotor; Ventricular fibrillation; Recovery of function
资金
- NIH [R01 HD046442]
- Office of Research and Development, Medical Research Service, Department of Veterans Affairs
The nature of residual cognitive deficits after out of hospital cardiac arrest (OHCA) is incompletely described and has never been defined against a cardiac control (CC) group. The objective of this study is to examine neuropsychological outcomes 3 months after OHCA in patients in a. middle range of acute severity. Thirty prospective OHCA admissions, with coma > 1 day and responsive but confused at 1 week, and 30 non-OHCA coronary care admissions were administered standard tests in five cognitive domains. OHCA subjects fell into two deficit profiles. One group (N = 20) had mild memory deficits and borderline psychomotor deficits compared to the CC group; 40% had returned to work. The other group (N = 10) had severe impairments in all domains. Coma duration was associated with group. Neither group had a high prevalence of depression. For most patients within the middle range of acute severity of OHCA, cognitive and functional outcomes at 3 months were encouraging. (JINS, 2011, 17, 364-368)
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