期刊
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
卷 31, 期 1-2, 页码 29-41出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.jeurceramsoc.2010.08.011
关键词
Microstructure final; Hydroxyapatite; Rapid prototyping; Laser processing; Biomedical applications
资金
- Spanish Government
- FEDER [CICYT MAT2006-10481]
- FPU program [AP2006-03500]
- Galician Government [PGIDT06805 AY020031F, INCITE081R303002ES, INCITE09E2R303103ES]
Rapid prototyping based on laser cladding by powder Injection has been used to produce calcium phosphate three-dimensional grafts without using molds Precursor material comprising of hydroxyapatite (HA) powder was irradiated by means of an infrared Nd YAG laser The processing parameters and the thermal history of the processed material have been assessed and the process has been optimized to obtain solid parts Processing by laser cladding lead to complete dehydroxylation of the precursor HA the obtained microstructure is composed by an alpha-tricalcium phosphate (alpha TCP) matrix with nucleated a tracalcium phosphate (TTCP) grains, in coexistence with oxyapatite and amorphous calcium phosphate The produced bioceramic grafts were observed to be bioactive, leading to calcium-deficient hydroxyapatite precipitation and promoting pre-osteoblastic cell attachment and proliferation during 'in vitro cell culture test (C) 2010 Elsevier Ltd All rights reserved
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