期刊
POLYMER CHEMISTRY
卷 6, 期 1, 页码 143-149出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4py00967c
关键词
-
资金
- Major Project of Chinese National Programs for Fundamental Research and Development (973 Project) [2009CB930400, 2012CB933803]
- National Science Foundation for Distinguished Young Scholars [50925310]
- National Science Foundation of China [20874059, 21174087]
Low mechanical strength is a major disadvantage of injectable hydrogels. Although the mechanical properties of hydrogels can be improved by the introduction of robust materials, the use of conventional reinforcing agents limits the medical application of injectable hydrogels due to their non-biodegradable property. We synthesized and self-assembled an injectable hydrogel from biodegradable mixed-substituted polyphosphazene and the natural organic molecule alpha-cyclodextrin (alpha CD) by host-guest inclusion. Photo-crosslinking was then employed for the hydrogel to transform it into the solid state with the desired shape. By this approach, the mechanical properties and anti-water solubility of the polyphosphazene hydrogel can meet the requirements of potential applications. In addition, the surface of the cured hydrogel can be readily tuned from cell-philic to cell-phobic by changing the ratio of two side chains of substituted polyphosphazene.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据