期刊
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
卷 23, 期 10, 页码 1631-1634出版社
AMER SOC NEPHROLOGY
DOI: 10.1681/ASN.2011111078
关键词
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资金
- National Institutes of Health [RO1 DK087727, K08 DK-075846, RO1 DK-069533, RO1 DK-071837]
- Claffin Distinguished Scholar Award from the Massachusetts General Hospital
Anemia is a common feature of CKD associated with poor outcomes. The current management of patients with anemia in CKD is controversial, with recent clinical trials demonstrating increased morbidity and mortality related to erythropoiesis stimulating agents. Here, we examine recent insights into the molecular mechanisms underlying anemia of CKD. These insights hold promise for the development of new diagnostic tests and therapies that directly target the pathophysiologic processes underlying this form of anemia.
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