Serum Carotenoid and Tocopherol Concentrations Vary by Dietary Pattern among African Americans

Background Intakes and biochemical concentrations of carotenoids and tocopherols have been associated with chronic diseases. Objective To describe dietary patterns in Jackson Heart Study participants and to determine if biochemical measurements of antioxidants differ across these. Design Cross-sectional analysis of data for 373 African-American men and women (age 35 to 80 years), participating in the Diet and Physical Activity Substudy of the Jackson Heart Study. Methods Dietary intake was assessed with a region specific food frequency questionnaire. Patterns were defined by cluster analysis of food groups, as percent of energy intake. Results Four dietary patterns were identified: fast food, Southern, prudent, and juice. Individuals in the fast-food pattern (n = 153) had significantly lower serum concentrations of lutein plus zeaxanthin and beta-cryptoxanthin; those in the Southern cluster (n=99) had significantly lower serum a-carotene; and those in the prudent (n=63) and juice (n = 58) clusters had significantly higher serum a-carotene and beta-cryptoxanthin (P<0.05) relative to those in at least one other cluster (all P<0.05). The juice cluster also had higher serum a-tocopherol concentrations relative to the fast-food cluster. Conclusions Diets high in fast foods, snacks, soft drinks, and meat were associated with relatively low concentrations of carotenoids and a-tocopherol. This pattern contained the largest number of participants, and could contribute to the extensive health disparities seen in this region.