期刊
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
卷 27, 期 3, 页码 428-433出版社
AMER COLLEGE NUTRITION
DOI: 10.1080/07315724.2008.10719721
关键词
ascorbic acid; vitamins; supplementation; scurvy
资金
- Lotte and John Hecht Memorial Foundation
- Faculty of Medicine summer research bursary award
Objectives: There is almost no information regarding the vitamin C status of patients treated in Canadian and American hospitals. We determined the prevalence and predictors of vitamin C deficiency in patients hospitalized on the acute-care wards of a Canadian teaching hospital, and tracked their plasma vitamin C concentrations while they were there. Methods: This was a population-based cross-sectional and time course survey of 149 medical patients shortly after admission to a university teaching hospital. The procedure for sample handling, storage and analysis was validated by measuring the vitamin C concentrations of a reference sample of 141 presumably well nourished people and comparing the results with published norms. Results: In keeping with published norms, 13% of people in the reference group had a subnormal vitamin C concentration (< 28.4 mu mol/L) and 3% were vitamin C deficient (< 11.4 mu mol/L). By contrast, 60% of hospitalized patients had a subnormal vitamin C concentration and 19% were deficient. A history of inadequate nutrition or failure to use a vitamin supplement prior to admission, low serum albumin, and male sex predicted plasma vitamin C deficiency, whereas use of a vitamin supplement prior to admission was associated with adequate vitamin C status in hospital. In a second measurement, obtained in 52 patients after an average of 17 days in hospital, vitamin C status had not improved. Conclusions: Vitamin C deficiency is prevalent and Sustained in patients in a Canadian teaching hospital. The abnormality can be prevented by providing a diet sufficient in vitamin C or by prescribing a multiple vitamin tablet.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据