期刊
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
卷 57, 期 8, 页码 891-903出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jacc.2010.11.013
关键词
cardiac magnetic resonance; late gadolinium enhancement; myocardial fibrosis; T1 mapping
资金
- French Federation of Cardiology
- National Institutes of Health [P20HL101397]
Diffuse interstitial or replacement myocardial fibrosis is a common feature of a broad variety of cardiomyopathies. Myocardial fibrosis leads to impaired cardiac diastolic and systolic function and is related to adverse cardiovascular events. Cardiovascular magnetic resonance (CMR) may uniquely characterize the extent of replacement fibrosis and may have prognostic value in various cardiomyopathies. Myocardial longitudinal relaxation time mapping is an emerging technique that could improve CMR's diagnostic accuracy, especially for interstitial diffuse myocardial fibrosis. As such, CMR could be integrated in the monitoring and therapeutic management of a large number of patients. This review summarizes the advantages and limitations of CMR for the assessment of myocardial fibrosis. (J Am Coll Cardiol 2011; 57: 891-903) (C) 2011 by the American College of Cardiology Foundation
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