4.8 Article

Nickel-Catalyzed Stereoselective Diarylation of Alkenylarenes

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 140, 期 34, 页码 10653-10657

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AMER CHEMICAL SOC
DOI: 10.1021/jacs.8b05680

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资金

  1. NIH [5R01GM114443]
  2. China Scholarship Council
  3. National Natural Science Foundation of China [21602168]
  4. Indiana University

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A three-component coupling of aryl bromides, arylboron reagents, and alkenylarenes is presented. The method tolerates a variety of substitution patterns on all of the components. In particular, 1,2-disubstituted alkenylarenes are suitable and undergo highly diastereoselective diarylation.

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