期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 135, 期 34, 页码 12532-12535出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja405972h
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资金
- EPSRC
- Syngenta
- Marie Curie Foundation
- ERC
- EPSRC [EP/I00548X/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/I00548X/1] Funding Source: researchfish
Copper-catalyzed arylation of electron rich alkynes reveals stabilized trisubstituted vinyl cation equivalents that react with pendant arene nucleophiles to form all carbon tetrasubstituted alkenes. The new process streamlines the synthesis of important medicinally relevant molecules.
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