期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 135, 期 31, 页码 11517-11520出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja406135t
关键词
-
资金
- National Natural Science Foundation of China [21232006]
- State Basic Research Program of China [2009CB825300]
Three-carbon axial chirality has been asymmetrically established from racemic one-carbon central chirality efficiently at room temperature: we report here the discovery of the first catalytic asymmetric carbonylation of readily available racemic propargylic carbonates to access optically active 2,3-allenoates with fairly high ee. The combination of [(pi-allyl)PdCl](2) with [(R)-ECNU-Phos], a new chiral bisphosphine ligand based on a biphenyl skeleton, demonstrates high enantioselectivity. Both enantiomers of allenoates can be obtained at room temperature by applying either (R)- or (S)-ECNU-Phos.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据