期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 135, 期 25, 页码 9283-9286出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja403811t
关键词
-
资金
- NIH [R01 GM068650, 5T32GM008550]
- NSF [CHE 1300329]
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [1300329, 1229234] Funding Source: National Science Foundation
Enantiomerically enriched cyclobutanes are constructed by a three-component process in which t-butyl (E)-2-diazo-5-arylpent-4-enoates are treated with Rh2(S-NTTL)(4) to provide enantiomerically enriched bicyclobutanes, which can subsequently engage in homoconjugate addition/enolate trapping sequence to give densely functionalized cyclobutanes with high diastereoselectivity. This three-component, two-catalyst procedure can be carried out in a single flask. Rh-2(S-NTTL)(4)-catalyzed reaction of t-butyl (Z)-2-diazo-5-phenylpent-4-enoate gives the Buchner cyclization product in excellent enantioselectivity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据