期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 135, 期 44, 页码 16384-16387出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja409803x
关键词
-
资金
- JSPS [220GR049]
- MEXT [25105720, 25708005]
- JSPS
- World Premier International Research Center (WPI) Initiative, Japan
- Grants-in-Aid for Scientific Research [25708005, 25105720, 13J03280] Funding Source: KAKEN
We describe mechanistic studies of a C-H/C-O biaryl coupling of 1,3-azoles and aryl pivalates catalyzed by Ni(cod)(2)/dcype. This study not only supports a catalytic cycle consisting of C-O oxidative addition, C-H nickelation, and reductive elimination but also provides insight into the dramatic ligand effect in C-H/C-O coupling. We have achieved the first synthesis, isolation and structure elucidation of an arylnickel(II) pivalate, which is an intermediate in the catalytic cycle after oxidative addition of a C-O bond. Furthermore, kinetic studies and kinetic isotope effect investigations reveal that the C-H nickelation is the turnover-limiting step in the catalytic cycle.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据