期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 134, 期 40, 页码 16464-16467出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja305988f
关键词
-
资金
- Ministry of Knowledge Economy, South Korea
- Princess Margaret Hospital Foundation
- National Science and Engineering Research Council of Canada
- Canadian Institute for Health Research
- Canadian Foundation of Innovation
- Joey and Toby Tanenbaum/Brazilian Ball Chair in Prostate Cancer Research
- Ministry of Knowledge Economy (MKE), Republic of Korea [2010-TD-500409-001] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Porphyrin-phospholipid conjugates were used to create photonic microbubbles (MBs) having a porphyrin shell (porshe), and their acoustic and photoacoustic properties were investigated. The inclusion of porphyrin-lipid in the MB shell increased the yield, improved the serum stability, and generated a narrow volumetric size distribution with a peak size of 2.7 +/- 0.2 mu m. Using an acoustic model, we calculated the porshe stiffness to be 3-5 times greater than that of commercial lipid MBs. Porshe MBs were found to be intrinsically suitable for both ultrasound and photoacoustic imaging with a resonance frequency of 9-10 MHz. The distinctive properties of porshe MBs make them potentially advantageous for a broad range of biomedical imaging and therapeutic applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据