4.8 Article

Click-Functionalized Compact Quantum Dots Protected by Multidentate-Imidazole Ligands: Conjugation-Ready Nanotags for Living-Virus Labeling and Imaging

期刊

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 134, 期 20, 页码 8388-8391

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AMER CHEMICAL SOC
DOI: 10.1021/ja302367s

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资金

  1. National Basic Research Program of China (973 Program) [2011CB933600]
  2. National Natural Science Foundation of China [81071249, 20905050]
  3. Science and Technology Foundation of Guangdong Province of China [2009A030301010, 9478922035-X003399]
  4. Guangdong Innovation Reasearch Team of Low-cost Healthcare
  5. Shenzhen Key Laboratory of Cancer Nanotechnology
  6. Chinese Academy of Sciences

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We synthesized a new class of mutifunctional multidentate-imidazole polymer ligands by one-step reaction to produce conjugation-ready QDs with great stability and compact size. Furthermore, combined with strain-promoted click chemistry, we developed a general strategy for efficient labeling of living-viruses with QD probes.

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