期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 134, 期 8, 页码 3912-3916出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja212182q
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-
资金
- NIH [CA28824, CA062948]
Application of native chemical ligation logic to the case of an N-terminal proline is described. Two approaches were studied. One involved incorporation of a 3R-substituted thiyl-proline derivative. Improved results were obtained from a 3R-substituted selenol function, incorporated in the context of an oxidized dimer.
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