期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 134, 期 39, 页码 16099-16102出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja304373u
关键词
-
资金
- American Cancer Society [118198-IRG-58-001-52-IRG80]
- University of Minnesota
A molecular probe for the luminescent detection of adenosine nucleotides is presented. The probe, Tb-DOTAm-Phen, readily distinguishes among the three adenosine nucleotides in buffered aqueous conditions at neutral pH, a requirement for the direct monitoring of enzymatic reactions converting adenosine triphosphate (ATP) to adenosine diphosphate or adenosine monophosphate. The probe is most efficient under millimolar concentrations of ATP which are relevant to intracellular conditions. Moreover, the long luminescence lifetime of the probe readily enables time-gating experiments.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据