期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 134, 期 40, 页码 16558-16561出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja308876j
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资金
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- le Fonds Quebecois de la Recherche sur la Nature et les Technologies of Quebec (FQRNT)
- Canada Research Chairs Program
- Simon Fraser University through the Community Trust Endowment Fund
- FRQS
- Michael Smith Foundation for Health Research
- China Scholarship Council
Using a photosensitive hybrid hydrogel loaded with upconversion nanoparticles (UCNPs), we show that continuous-wave near-infrared (NIR) light (980 nm) can be used to induce the gel-sol transition and release large, inactive biomacromolecules (protein and enzyme) entrapped in the hydrogel into aqueous solution on demand, where their bioactivity is recovered. This study is a new demonstration and development in harnessing the unique multiphoton effect of UCNPs for photosensitive materials of biomedical interest.
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