期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 135, 期 1, 页码 2-5出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja3069177
关键词
-
资金
- Australian Research Council (ARC)
- National Health and Medical Research Council (NHMRC)
We developed a new genetic selection approach to screen for mutations that can alter the efficiency of selenocysteine incorporation. We identified mutations in 16S rRNA that increase or decrease the efficiency of selenocysteine incorporation in Escherichia coli without influencing the efficiency or fidelity of canonical translation. Engineered ribosomes with improved selenocysteine incorporation provide valuable tools for synthetic biology and biotechnology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据