期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 134, 期 18, 页码 7676-7678出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja3002277
关键词
-
资金
- Swiss National Science Foundation
- EPFL
We report the semisynthesis of a fluorescent glutamate sensor protein on cell surfaces. Sensor excitation at 547 nm yields a glutamate-dependent emission spectrum between 550 and 700 nm that can be exploited for ratiometric sensing. On cells, the sensor displays a ratiometric change of 1.56. The high sensitivity toward glutamate concentration changes of the sensor and its exclusive extracellular localization make it an attractive tool for glutamate sensing in neurobiology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据