期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 133, 期 10, 页码 3339-3341出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja109824x
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资金
- National Institutes of Health (NIH) [GM-082935]
- National Science Foundation [NSF-0847108]
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [0847108] Funding Source: National Science Foundation
We disclose a novel high yielding and highly enantioselective chiral calcium VAPOL phosphate-catalyzed chlorination of 3-substituted oxindoles with N-chlorosuccinimide (NCS). The reaction conditions are also shown to be effective for the catalytic enantioselective Michael addition of 3-aryloxindoles to methyl vinyl ketone.
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