期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 133, 期 11, 页码 3740-3743出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja1108694
关键词
-
资金
- National Basic Research Program of China [2009CB825300]
- National Natural Science Foundation of China [20732005, J0830413]
An efficient method for synthesis of polysubstituted cyclobutenones, which are not readily available from traditional methods due to the intrinsic ring strain, is described. The reaction of 2,3-allenoates and organozinc reagents proceeds via a tandem Michael addition/cyclic 1,2-addition/elimination mechanism with the functional groups from the organozinc reagents being introduced to the 3-position of the cyclobutenone products regiospecifically in moderate to excellent yields. Application to the synthesis of stereodefined beta,gamma-unsaturated enones is demonstrated.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据