Pd-Catalyzed Three-Component Coupling of N-Tosylhydrazone, Terminal Alkyne, and Aryl Halide

A Pd-catalyzed three-component reaction of N-tosylhydrazone, terminal alkyne, and aryl halide follows a mechanism involving a sequence of Pd carbene migratory insertion-trans-metalation reductive elimination, leading to the formation of one sp(2)-sp(3) C-C bond and one sp-sp(3) C-C bond.