期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 132, 期 37, 页码 12829-12831出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja105563a
关键词
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资金
- National Institutes of Health [RR02584, CA115531, CA126608]
The synthesis of a polylysine dendron containing eight GdDOTA units conjugated to a peptoid dimer known to have a high affinity for the vascular endothelial growth factor receptor 2 (VEGFR2) is described. This simple low molecular weight system with a molecular r(1) relaxivity of similar to 48 mM(-1) s(-1) shown to enhance MR images of tumors grown in mice in vivo.
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