期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 132, 期 16, 页码 5544-+出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja9104057
关键词
-
资金
- Natural Sciences and Engineering Research Council (NSERC) of Canada
- University of Alberta
- Queen Elizabeth II Graduate Scholarship
There is a growing interest in the development of new methods to prepare chiral organoboronate derivatives in optically pure form. An efficient copper-catalyzed enantioselective conjugate addition methodology using Grignard reagents and 3-boronyl acrylate derivatives was optimized for the preparation of chiral alkylboronate products in high yields and up to 98% ee. The resulting 1,8-diaminonaphthalene adducts can be transformed into the corresponding boronic acid, pinacol boronate, and trifluoroborate salt. This method extends the realm of chemical reactions compatible with useful boron-containing substrates.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据