期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 132, 期 21, 页码 7466-7471出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja102042p
关键词
-
资金
- Swiss National Foundation [200020-117617]
Oligopyrenotides, abiotic oligomers that exhibit significant structural analogies to the nucleic acids, are described. They are composed of achiral, phosphodiester-linked pyrene building blocks and a single chiral 1,2-diaminocyclohexane unit. These oligomers form stable hybrids in aqueous solution. Hybridization is based on stacking interactions of the pyrene building blocks. They show thermal denaturation/renaturation behavior that closely resembles DNA and RNA hybridization. In addition, oligopyrenotides display salt-concentration-dependent structural polymorphism. Thus, they possess a number of structural attributes that are typical of nucleic acids and therefore may serve as model systems for the design of artificial self-replicating systems.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据