期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 132, 期 37, 页码 12841-12843出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja1054912
关键词
-
资金
- CNRS
A very simple, one-step highly diastereoselective synthesis of bulky, configurationally and air-stable P-chiral tricyclic phosphines 3, showing an exceptionally strong nucleophilic character, has been developed. This method involves the reaction of the stable phosphonium sila-ylide 1 with aryl- and alkyl-substituted acetylene derivatives. Starting from commercially available chiral (R,S)-(+)-endo-2-norborneol, the corresponding enantiomerically pure phosphines were obtained with excellent enantioselectivities (ee >= 99%) and high chemical yields.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据