4.8 Article

Potential Oxidative Stress of Gold Nanoparticles by Induced-NO Releasing in Serum

期刊

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 131, 期 1, 页码 40-+

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AMER CHEMICAL SOC
DOI: 10.1021/ja808033w

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资金

  1. National Natural Science Foundation of China [30570446, 20875093]
  2. 863 program [2007AA10Z352]
  3. Institute of Chemistry Chinese Academy of Sciences [CMS-Y200712]

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Nitric oxide (NO)-release in blood serum initiated by gold nanoparticles has been prove to be a reaction between RSNO and the gold nanoparitctes. In this reaction the NO production was catalyzed on the surface of the nanoparticles, and a new bond of Au-thiolate was simultaneously formed.

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