4.8 Article

An Aromatic Glaser-Hay Reaction

期刊

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 131, 期 47, 页码 17052-+

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AMER CHEMICAL SOC
DOI: 10.1021/ja907479j

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资金

  1. Welch Foundation [E-1571]
  2. National Institute of General Medical Sciences [R01GM077635]
  3. A. P. Sloan Foundation, Camille
  4. Henry Dreyfus Foundation
  5. Norman Hackerman Advanced Research Program

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A general method for copper-catalyzed deprotonative dimerization of arenes by employing oxygen as the terminal oxidant has been developed. Electron-rich and electron-poor heterocycles as well as electron-poor arenes are reactive. The method is tolerant to functionalities such as nitro, cyano, dialkylamino, and ester groups.

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