期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 131, 期 12, 页码 4198-+出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja900174t
关键词
-
资金
- Japan Society for Promotion in Science (JSPS)
- Uehara Memorial Foundation
ortho-Alkynylphenylureas and -acetamides 1, with an alkoxy and aryl group on the nitrogen atom, were subjected to platinum-catalyzed cyclization reactions to afford the corresponding tetracyclic compounds 2, via N-O bond cleavage, in good to excellent yields. For example, N-methoxy-N'-methyt-N'-(2-(pent-1-ynyl)phenyl)-N-phenylurea (1a) was reacted for 12 h in the presence of Ptl(4) (10 mol%) in 1,4-dioxane at 100 degrees C to afford 5-methyl-12-propytindolo[1,2-c]quinazolin-6(5H)-one (2a) in 93% yield, via an iminium-bound platinum carbenoid intermediate, followed by an aromatic C-H insertion.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据