期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 131, 期 5, 页码 1678-+出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja809280r
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资金
- ESPRC Platform [GR/S77721]
- Chemical Biology Centre (Imperial College London)
- EPSRC [EP/G00465X/1] Funding Source: UKRI
- STFC [ST/F001401/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/G00465X/1] Funding Source: researchfish
- Science and Technology Facilities Council [ST/F001401/1] Funding Source: researchfish
Lipids that are found in cell membranes form a variety of self-assembled phases in the presence of water. Many of these structures are liquid-crystalline with structural motifs mirrored in cells and organelles and can be exploited in the delivery of drugs and genes. We report the discovery of a lyotropic liquid crystalline phase based on a 3-D hexagonal close-packed arrangement of inverse micelles, of space group P6(3)/mmc. This is the first new inverse lyotropic liquid-crystalline phase to be reported for two decades and is the only known lyotropic phase whose structure consists of a close packing of identical inverse micelles.
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