期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 130, 期 30, 页码 9652-+出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja803520q
关键词
-
Intermolecular sensitization of lanthanide ions was effectively implemented in the development of fluorescent sensors targeting cyclin A. A chelating unit has been conjugated to peptides containing a known cyclin A binding motif (CBM). Upon interaction of the modified terbium-chelating peptides with the cyclin A substrate recruitment groove, the Tb3+ ion is placed in the vicinity of the Trp(217) side chain, which results in efficient intermolecular terbium sensitization and specific long wavelength fluorescent emission from the metal center.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据