期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 130, 期 3, 页码 810-+出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja710294k
关键词
-
资金
- NIGMS NIH HHS [R01 GM31332-05, R01 GM080269, R01 GM080269-01] Funding Source: Medline
Described in this report is the first total synthesis of elatol, a halogenated sesquiterpene in the chamigrene natural product family. The key disconnections in our synthetic approach include an enantioselective decarboxylative allylation to form the all-carbon quaternary stereocenter and a ring-closing olefin metathesis to concomitantly form the spirocyclic core as well as the fully substituted chlorinated olefin. This strategy represents a general platform for accessing the chamigrene natural product family, as demonstrated by the synthesis of (+)-laurencenone B as an intermediate in our route.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据