期刊
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
卷 60, 期 2, 页码 315-320出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.jaad.2008.08.035
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Epidermodysplasia verruciformis (EV) is a rare autosomal recessive genodermatosis with an increased susceptibility to Specific human papillomavirus (HPV) genotypes. Classically, this viral infection leads to the development of: tinea versicolor-like macules on the trunk, neck, arms, and face during Childhood, and over time, these lesions can progress to squamous Cell carcinoma. More recently, an EV-like syndrome has been described in patients with impaired cell-mediated immunity. We describe two cases of EV-like syndrome in HIV-positive patients, review all previously reported cases of EV in patients with impaired cell-mediated immunity, introduce the term acquired epidermodysplasia verruciformis to describe EV developing in the immunocompromised host and examine the limited treatment options for these patients. (J Am Acad Dermatol 2009-160:315-20.)
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