期刊
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
卷 136, 期 3, 页码 1077-1084出版社
ACOUSTICAL SOC AMER AMER INST PHYSICS
DOI: 10.1121/1.4890643
关键词
-
资金
- Ministry of Economy of Spain [DPI2011-28356-C03-01]
- National Science Foundation [CBET 1134420]
- Div Of Chem, Bioeng, Env, & Transp Sys
- Directorate For Engineering [1134420] Funding Source: National Science Foundation
The acoustic attenuation spectrum of lipid-coated microbubble suspensions was measured in order to characterize the linear acoustic behavior of ultrasound contrast agents. For that purpose, microbubbles samples were generated with a very narrow size distribution by using microfluidics techniques. A performance as good as optical characterization techniques of single microbubbles was achieved using this method. Compared to polydispersions (i.e., contrast agents used clinically), monodisperse contrast agents have a narrower attenuation spectrum, which presents a maximum peak at a frequency value corresponding to the average single bubble resonance frequency. The low polydispersity index of the samples made the estimation of the lipid viscoelastic properties more accurate since, as previously reported, the shell linear parameters may change with the equilibrium bubble radius. The results showed the great advantage of dealing with monodisperse populations rather than polydisperse populations for the acoustic characterization of ultrasound contrast agents. (C) 2014 Acoustical Society of America.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据