期刊
JOURNAL OF SYNCHROTRON RADIATION
卷 19, 期 -, 页码 525-529出版社
WILEY-BLACKWELL
DOI: 10.1107/S0909049512017682
关键词
medical X-ray imaging; phase contrast; inverse Compton X-rays
资金
- DFG Cluster of Excellence Munich, Centre for Advanced Photonics
- European Research Council [240142]
- NIGMS [R44-GM074437]
- NCRR [R43-RR025730]
The Compact Light Source is a miniature synchrotron producing X-rays at the interaction point of a counter-propagating laser pulse and electron bunch through the process of inverse Compton scattering. The small transverse size of the luminous region yields a highly coherent beam with an angular divergence of a few milliradians. The intrinsic monochromaticity and coherence of the produced X-rays can be exploited in high-sensitivity differential phase-contrast imaging with a grating-based interferometer. Here, the first multimodal X-ray imaging experiments at the Compact Light Source at a clinically compatible X-ray energy of 21 keV are reported. Dose-compatible measurements of a mammography phantom clearly demonstrate an increase in contrast attainable through differential phase and dark-field imaging over conventional attenuation-based projections.
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