期刊
JOURNAL OF SURGICAL ONCOLOGY
卷 109, 期 4, 页码 383-388出版社
WILEY-BLACKWELL
DOI: 10.1002/jso.23474
关键词
isolated hepatic perfusion; percutaneous hepatic perfusion; melphalan
资金
- Delcath Systems, Inc
Unresectable hepatic metastases from melanoma present a challenge to the physician. Although there have been advances in systemic therapies for patients with metastatic cutaneous melanoma to the liver, the overall prognosis is poor and is worse in patients with metastatic ocular melanoma. Isolated hepatic perfusion, open or percutaneous, allows high doses of cytotoxic chemotherapy to be delivered directly to the liver while minimizing systemic exposure, and has emerged as a viable treatment options for these complex patients. J. Surg. Oncol. 2014 109:383-388. (c) 2013 Wiley Periodicals, Inc.
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