Treatment of Metastatic Melanoma with Electrochemotherapy

Superficially metastatic melanoma still represents a challenging situation for oncologists and a distressing condition for patients. In this circumstance, local treatment by electrochemotherapy, that is, the combination of brief permeabilizing electric pulses with a low-toxicity anticancer drug, can be a valuable treatment option in selected patients who are ineligible/refractory to systemic treatments or require rapid palliation of symptomatic cutaneous disease. J. Surg. Oncol. 2014 109:301-307. (c) 2013 Wiley Periodicals, Inc.