期刊
JOURNAL OF SURGICAL ONCOLOGY
卷 106, 期 6, 页码 757-764出版社
WILEY-BLACKWELL
DOI: 10.1002/jso.23141
关键词
gastric; mucinous; carcinoma; histology; prognosis; HER2; EGFR
资金
- Korea Healthcare Technology R&D Project, Ministry for Health & Welfare Affairs, Republic of Korea [A092255, A101130]
- Samsung Biomedical Research Institute [SBRI-CB11031]
- Korea Health Promotion Institute [A101130] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Background Mucinous gastric carcinoma (MGC) is a distinct histologic subtype of gastric cancer. However, the prognostic significances of the current TNM staging system and histology in MGC have not been studied. Methods 206 patients who underwent R0 resection for MGC were classified by tumor size (<3?cm as T1; =35?cm as T2; =59?cm as T3; and =9?cm as T4). Immunohistochemistry for EGFR and HER2 was also performed. Results Tumor sizes ranged from 1.2 to 21.0?cm (median 6.2?cm). Large tumor size (=5?cm) was significantly associated with older patient age, deeper invasion depth, and more frequent lymph node metastasis (P?
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