期刊
JOURNAL OF SURGICAL ONCOLOGY
卷 104, 期 6, 页码 613-616出版社
WILEY
DOI: 10.1002/jso.21891
关键词
papillary thyroid cancer; ultrasound; lymph node metastases; predictors
资金
- NIDCR NIH HHS [P50 DE019032] Funding Source: Medline
Background and Objectives: Lymph node metastases in papillary thyroid cancer (PTC) are common and their presence can significantly alter the treatment for patients with PTC. We therefore sought to identify pre-operative predictors of lymph node metastases in patients with PTC. Methods: A thyroid tumor database was queried to identify patients with a pre-operative diagnosis of PTC and underwent thyroidectomy between January 2006 and August 2009. One hundred and three patients who had a pre-operative ultrasound and had lymph nodes surgically resected were identified. Clinical factors and tumor ultrasound characteristics were recorded. The pre-operative ultrasound results, type of operation, and final pathology results were also recorded. Results: Of the 103 patients, 74 (72%) were women and 29 (28%) were men with an age range of 15-78 years (median age of 43). Of the ultrasound characteristics evaluated only calcifications (P = 0.007) and size (P = 0.003) were statistically associated with positive cervical lymph nodes. None of the other demographic or clinical factors were significantly associated with lymph node metastases. Conclusions: Thyroid nodule size and presence of calcifications on ultrasound were found to have a statistically significant association with lymph node metastases in patients with PTC. This information could be used to guide the surgical management of these patients. J. Surg. Oncol. 2011;104:613-616. (C) 2011 Wiley Periodicals, Inc.
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