Supercritical fluids processing of polymers for pharmaceutical and medical applications

A critical analysis is presented of the supercritical fluids based technologies that have been proposed in polymer processing for pharmaceutical and medical applications. The formation of polymer-drug microparticles and microspheres, the production of simple or loaded membranes and the formation of temporary scaffolds are reviewed and the future trends in these areas are analyzed. (C) 2008 Elsevier B.V. All rights reserved.