期刊
PLANT SCIENCE
卷 241, 期 -, 页码 1-10出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.plantsci.2015.09.014
关键词
Sulfate assimilation; Systems biology; Genome wide association; Glucosinolates; Glutathione
资金
- Deutsche Forschungsgemeinschaft [EXC 1028]
- Biotechnology and Biological Sciences Research Council (BBSRC) [BB/J004561/1]
- John Innes Foundation
- Biotechnology and Biological Sciences Research Council [1242998] Funding Source: researchfish
Sulfur is an essential mineral nutrient for plants, therefore, the pathways of its uptake and assimilation have been extensively studied. Great progress has been made in elucidation of the individual genes and enzymes and their regulation. Sulfur assimilation has been intensively investigated by -omics technologies and has been target of several genome wide genetic approaches. This brought a significant step in our understanding of the regulation of the pathway and its integration in cellular metabolism. However, the large amount of information derived from other experiments not directly targeting sulfur has also brought new and exciting insights into processes affecting sulfur homeostasis. In this review we will integrate the findings of the targeted experiments with those that brought unintentional progress in sulfur research, and will discuss how to synthesize the large amount of information available in various repositories into a meaningful dissection of the regulation of a specific metabolic pathway. We then speculate how this might be used to further advance knowledge on control of sulfur metabolism and what are the main questions to be answered. (C) 2015 The Authors. Published by Elsevier Ireland Ltd.
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