Synthesis of silicated hydroxyapatite Ca10(PO4)6-x(SiO4)x(OH)2-x

The preparation of silicated hydroxyapatite Ca-10(PO4)(6-x)(SiO4)(x)(OH)(2-x) (SiHA) with 0 <= x <= 2 was investigated using a wet precipitation method followed by a heat treatment. X-ray diffraction and Rietveld refinement, Fourier transformed IR (FTIR) spectroscopy, elemental analyses, transmission electron microscopy and thermal analyses were used to characterize the samples. The raw materials were composed of a partially silicated and carbonated apatite and a secondary minor phase containing the excess silicon. Single phase silicated hydroxyapatites, with 0 <= x <= 1, could be synthesized after a thermal treatment of the raw powders above 700 degrees C. The presence of carbonate groups in the raw apatite played an important role in the incorporation of silicates during heating. From the different results, the mechanisms of formation of SiHA are discussed. (C) 2008 Elsevier Inc. All rights reserved.