期刊
JOURNAL OF SEPARATION SCIENCE
卷 42, 期 1, 页码 38-50出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.201800891
关键词
kinetic performance; kinetic plot; ultra high performance liquid chromatography; ultra high pressure liquid chromatography; van Deemter curve
资金
- Research Foundation Flanders (FWO) [G025916N, 12J6517N, 1508914N]
yThis review describes chromatographic dispersion and different plate-height models frequently used to assess the chromatographic performance of ultra-high-pressure liquid chromatography column technology. Furthermore, different performance indices, including the resolution, the separation impedance, and kinetic plots are discussed allowing to quantify and visualize the resolving power in liquid chromatography. The construction of kinetic plots is explained, and different visualization approaches are highlighted. Finally, key instrument and column-technology developments to advance the kinetic performance limits are discussed and selected state-of-the-art applications are highlighted.
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