期刊
JOURNAL OF SEPARATION SCIENCE
卷 32, 期 19, 页码 3274-3277出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.200900236
关键词
Chiral imprinted polymer; Surface imprinting
资金
- Swedish Center for BioSepararion
Molecularly imprinted polymers (MIPs) are tailor-made materials that can specifically rebind desired target molecules. Usually, the template is in solution with monomers that form a specific polymeric cavity around the template. Here, a model system with an amino acid (Fmoc-L-Histidine) is presented. This new approach entails the imprinting of templates that are bound to support materials. It is shown that the new approach leads to materials that exhibit symmetric peak shapes for both enantiomers under isocratic conditions.
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